Description

Boc-3-(3'-Quinolyl)-L-Alanine is a protected, non-proteinogenic amino acid derivative featuring a quinoline moiety. This compound is a crucial building block in modern pharmaceutical research, particularly in the synthesis of complex peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate the unique 3-quinolyl-alanine residue into peptide chains.
• Medicinal Chemistry: Serves as a scaffold for creating compound libraries to screen for biological activity against various targets.
• Proteomics Research: Employed in the study of protein structure and function, and in designing enzyme inhibitors.
• Bioconjugation: The Boc-protected amine and carboxylic acid groups allow for selective conjugation in bioconjugate chemistry.

Basic Information

Product Name	Boc-3-(3'-Quinolyl)-L-Alanine
CAS No.	135101-20-1
Molecular Formula	C₁₇H₂₀N₂O₄
Molecular Weight	316.36 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3-(3-quinolyl)-L-alanine; Boc-3-(3-Quinolyl)-L-Ala-OH; (2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(quinolin-3-yl)propanoic acid; tert-Butyl (2S)-2-amino-3-(quinolin-3-yl)propanoate, N-Boc derivative; Boc-L-3-(3-Quinolyl)alanine; N-Boc-3-(3-quinolyl)-L-alanine; 3-(3-Quinolyl)-L-alanine, N-Boc-; BOC-3-(3-QUINOLYL)-L-ALANINE
EINECS	Contact for details

Quality Control

Our Boc-3-(3'-Quinolyl)-L-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.