Description

Boc-3-(3'-Quinolyl)-D-Alanine is a protected, non-natural amino acid derivative featuring a quinoline moiety. This compound is a crucial chiral building block in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, medicinal chemistry, and the synthesis of complex heterocyclic compounds. The Boc (tert-butoxycarbonyl) protecting group offers orthogonal deprotection strategies, making it a versatile intermediate for solid-phase and solution-phase peptide synthesis.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, especially those targeting neurological or oncological pathways.
• Peptide Synthesis: Used in the construction of non-natural peptides and peptidomimetics where the quinoline side chain can impart specific binding or fluorescent properties.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Bioconjugation: Potential use in creating labeled peptides or protein conjugates for diagnostic or biochemical research applications.
• Chemical Biology Probes: Incorporation into molecules designed to study biological processes, leveraging the spectroscopic properties of the quinoline group.

Basic Information

Product Name	Boc-3-(3'-Quinolyl)-D-Alanine
CAS No.	135101-19-8
Molecular Formula	C₁₇H₂₀N₂O₄
Molecular Weight	316.36 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3-(quinolin-3-yl)-D-alanine; Boc-D-3-(3-Quinolyl)alanine; (R)-2-((tert-Butoxycarbonyl)amino)-3-(quinolin-3-yl)propanoic acid; tert-Butyl ((R)-1-carboxy-2-(quinolin-3-yl)ethyl)carbamate; Boc-D-Ala(3-Quin)-OH; BOC-D-3-Quinolyl-Ala-OH; D-Boc-3-Quinolylalanine
EINECS	Contact for details

Quality Control

Our Boc-3-(3'-Quinolyl)-D-Alanine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical development. A detailed Certificate of Analysis (COA) providing HPLC purity, chiral purity, and spectroscopic identification data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is sensitive to strong acids and should be kept away from oxidizing agents. For long-term storage, consider storing under an inert atmosphere in a freezer (-20°C).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.