Description

D-Alanine, n-[(2-Aminocyclopentyl)Carbonyl]-, (1R-Cis)- (9Ci) is a specialized, high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. This compound matters for its precise stereochemistry and functional groups, which are critical for constructing complex molecules with defined biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly peptidomimetics and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for metabolic and neurological targets.
• Peptidomimetic Research: Used to design and synthesize peptide analogs with enhanced stability, bioavailability, and specificity for drug discovery programs.
• Enzyme Inhibitor Development: Serves as a core structural component in creating potent and selective inhibitors for proteases and other enzymes.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways and mechanisms of action.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in catalytic asymmetric reactions to introduce chiral centers.
• Academic & Contract Research: A valuable reagent for methodological studies in synthetic organic chemistry and medicinal chemistry at universities and CROs.

Basic Information

Product Name	D-Alanine, n-[(2-Aminocyclopentyl)Carbonyl]-, (1R-Cis)- (9Ci)
CAS No.	135097-03-9
Molecular Formula	C9H16N2O3
Molecular Weight	200.24 g/mol
Synonyms	D-Alanine, N-[(2-aminocyclopentyl)carbonyl]-, (1R-cis)-; (1R,2S)-2-[(2-Aminocyclopentyl)carbonylamino]propanoic acid; (1R-cis)-N-[(2-Aminocyclopentyl)carbonyl]-D-alanine; cis-2-[(2-Aminocyclopentyl)carbonylamino]propanoic acid (D-form); A chiral alanine-derived cyclopentylamide
EINECS	Contact for details

Quality Control

Our D-Alanine, n-[(2-Aminocyclopentyl)Carbonyl]-, (1R-Cis)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.