Description

n-(2-Chloro-4-Iodophenyl)Acetamide is a halogenated aromatic acetamide derivative, serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its distinct molecular structure, featuring both chloro and iodo substituents, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical R&D teams engaged in medicinal chemistry, agrochemical development, and materials science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and oncological pathways.
• Agrochemical Research: Used in developing new generations of herbicides and fungicides, where the halogenated aromatic core contributes to biological activity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for advanced polymers and liquid crystals, where the iodine atom can be leveraged for further functionalization or to modify material properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	n-(2-Chloro-4-Iodophenyl)Acetamide
CAS No.	135050-05-4
Molecular Formula	C8H7ClINO
Molecular Weight	295.51 g/mol
Synonyms	2'-Chloro-4'-iodoacetanilide; N-(2-Chloro-4-iodophenyl)acetamide; Acetamide, N-(2-chloro-4-iodophenyl)-; 2-Chloro-4-iodoacetanilide; 2-Chloro-4-iodo-N-phenylacetamide; 135050-05-4; N-Acetyl-2-chloro-4-iodoaniline
EINECS	Contact for details

Quality Control

Our n-(2-Chloro-4-Iodophenyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity synthetic intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.