Description

2-Azabicyclo[2.2.1]Heptane-3-Carboxamide,(1S-Endo)-(9Ci) is a high-purity, stereochemically defined bicyclic lactam building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional scaffold is highly valuable for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and catalyst design.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disease research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and library synthesis to explore new chemical space due to its constrained conformation.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in enantioselective catalysis.
• Agrochemical Research: Employed in the design and synthesis of new generation herbicides and pesticides with improved selectivity.
• Academic & Institutional R&D: A valuable tool compound for methodological development in organic synthesis and total synthesis of natural products.
• Peptidomimetics: The bicyclic lactam structure is utilized to create conformationally restricted peptide analogs for biochemical studies.

Basic Information

Product Name	2-Azabicyclo[2.2.1]Heptane-3-Carboxamide,(1S-Endo)-(9Ci)
CAS No.	134929-66-1
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	(1S,2R,4S)-2-Azabicyclo[2.2.1]heptane-3-carboxamide; (1S-endo)-2-Azabicyclo[2.2.1]heptane-3-carboxamide; endo-(1S)-2-Azabicyclo[2.2.1]heptane-3-carboxamide; 2-Azabicyclo[2.2.1]heptane-3-carboxamide, (1S,2R,4S)-; Bicyclic Lactam Derivative; 2-Azanorbornane-3-carboxamide
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[2.2.1]Heptane-3-Carboxamide,(1S-Endo)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.