Description

Corticotropin Releasing Factor-Binding Protein CAS NO 134773-81-2 is a specific binding protein that modulates the activity of corticotropin-releasing factor (CRF), a key neuropeptide in the stress response system. This compound is essential for advanced research into the hypothalamic-pituitary-adrenal (HPA) axis, neurological disorders, and stress-related pathologies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers focused on endocrinology and neuroscience.

Application

• Neuroscientific Research: Critical for studying the regulation of the HPA axis, stress response mechanisms, and related behavioral models.
• Drug Discovery & Development: Serves as a key reagent and target in the development of novel therapeutics for anxiety, depression, and metabolic disorders.
• Biochemical Assay Development: Used as a standard or binding agent in ELISA, radioimmunoassays (RIA), and other in vitro diagnostic test development.
• Academic & Clinical Studies: Supports fundamental research into the role of CRF in physiology and disease states.
• Peptide Interaction Studies: Employed to investigate protein-peptide interactions and signal transduction pathways involving CRF receptors.

Basic Information

Product Name	Corticotropin Releasing Factor-Binding Protein
CAS No.	134773-81-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CRF-Binding Protein; CRF-BP; CRH-Binding Protein; Corticotropin-Releasing Hormone Binding Protein; CRH-BP; CRF Binding Protein (human); CRFBP
EINECS	Contact for details

Quality Control

Our Corticotropin Releasing Factor-Binding Protein is produced and handled under stringent quality management systems. Each batch undergoes rigorous analytical testing, including purity assessment by HPLC and identity confirmation, to ensure consistency and reliability for research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain integrity. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Biological Activity	Confirmed by binding assay
Endotoxin Level	< 1.0 EU/μg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.