Description

3-(2,4-Difluoro-Phenyl)-Acrylic Acid Ethyl Ester is a high-purity fluorinated acrylate ester building block, essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its difluorophenyl and acrylate moieties impart unique biological activity and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and liquid crystals with tailored properties.
• Organic Synthesis Reagent: Employed in Michael additions, cycloadditions, and other C-C bond-forming reactions to introduce the 2,4-difluorophenylacrylic acid moiety.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on molecular reactivity and interaction.
• Fine Chemical Production: Integral to the manufacture of dyes, pigments, and other performance chemicals requiring specific fluorinated structures.

Basic Information

Item	Detail
Product Name	3-(2,4-Difluoro-Phenyl)-Acrylic Acid Ethyl Ester
CAS No.	134672-68-7
Molecular Formula	C11H10F2O2
Molecular Weight	212.19 g/mol
Synonyms	Ethyl 3-(2,4-Difluorophenyl)acrylate; 2,4-Difluorocinnamic Acid Ethyl Ester; Ethyl (2E)-3-(2,4-Difluorophenyl)prop-2-enoate; (E)-Ethyl 3-(2,4-difluorophenyl)acrylate; 3-(2,4-Difluorophenyl)-2-propenoic Acid Ethyl Ester; NSC 339242; AI3-52021
EINECS	Contact for details

Quality Control

Our 3-(2,4-Difluoro-Phenyl)-Acrylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent isomeric composition. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isomeric Purity (GC/HPLC)	≥ 99.0% (E-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.