Description

2-Bromo-5-Nitrobenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an electron-withdrawing nitro group and a bromine substituent, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex aromatic dyes and colorants due to its nitro and cyano functional groups.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and creating compound libraries for high-throughput screening.

Basic Information

Product Name	2-Bromo-5-Nitrobenzonitrile
CAS No.	134604-07-2
Molecular Formula	C7H3BrN2O2
Molecular Weight	227.02 g/mol
Synonyms	5-Nitro-2-bromobenzonitrile; 2-Bromo-5-nitrobenzenecarbonitrile; Benzonitrile, 2-bromo-5-nitro-; 2-Bromo-5-nitro-benzonitrile; 2-Bromo-5-cyanobenzonitrile (incorrect but common); 2-Bromo-5-nitro-phenyl cyanide
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Nitrobenzonitrile is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.