Description

Carbamic Acid, (2-Methyl-3-Azabicyclo[3.1.0]Hex-6-Yl)-, 1,1-Dimethylethyl Ester is a specialized bicyclic carbamate derivative, serving as a crucial protected intermediate in advanced organic synthesis. Its value lies in its unique azabicyclo[3.1.0]hexane scaffold, which is a key structural motif for developing novel pharmaceuticals and bioactive compounds. This high-purity building block is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create complex molecules with specific stereochemistry and biological activity.

Application

• Pharmaceutical Intermediate: A key protected synthon for the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS).
• Agrochemical Research: Used in the development of novel pesticides and herbicides that leverage its constrained bicyclic structure.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Asymmetric Synthesis: Utilized in chiral synthesis due to the stereogenic centers present in its fused ring system.
• Peptidomimetics Development: Acts as a rigid, non-peptide backbone component in the design of peptide mimics for drug discovery.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical space in organic chemistry.

Basic Information

Item	Details
Product Name	Carbamic Acid, (2-Methyl-3-Azabicyclo[3.1.0]Hex-6-Yl)-, 1,1-Dimethylethyl Ester
CAS No.	134575-28-3
Molecular Formula	C12H21NO2
Molecular Weight	211.30 g/mol
Synonyms	tert-Butyl (2-methyl-3-azabicyclo[3.1.0]hex-6-yl)carbamate; (2-Methyl-3-azabicyclo[3.1.0]hex-6-yl)carbamic acid tert-butyl ester; N-Boc-2-methyl-3-azabicyclo[3.1.0]hexan-6-amine; 6-[(tert-Butoxycarbonyl)amino]-2-methyl-3-azabicyclo[3.1.0]hexane; Bicyclo[3.1.0]hexane-6-carboxamide derivative; Protected 3-azabicyclo[3.1.0]hexane amine; CAS 134575-28-3
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, (2-Methyl-3-Azabicyclo[3.1.0]Hex-6-Yl)-, 1,1-Dimethylethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.