Description

Leukocyte Common Antigen-Related Peptide CAS NO 134549-71-6 is a synthetic peptide sequence related to the leukocyte common antigen (LCA, CD45) receptor, a critical transmembrane protein tyrosine phosphatase involved in immune cell signaling. This compound is of significant value for researchers and developers in immunology and drug discovery, serving as a precise tool for studying T-cell and B-cell activation pathways. It is primarily needed by biotechnology, pharmaceutical R&D, and diagnostic reagent manufacturers focused on autoimmune diseases, cancer immunotherapy, and fundamental immunological research.

Application

• Immunological Research: Used as a reference standard or antigen in studies of T-cell receptor (TCR) and B-cell receptor (BCR) signaling mechanisms.
• Antibody Production & Validation: Serves as an immunogen for generating and screening monoclonal or polyclonal antibodies specific to CD45 epitopes.
• Diagnostic Development: Employed in the development and calibration of ELISA, Western blot, or other immunoassays for detecting CD45-related biomarkers.
• Drug Discovery Platforms: Integrated into high-throughput screening assays to identify potential modulators of CD45 phosphatase activity for therapeutic intervention.
• Cell Signaling Studies: Applied in vitro to investigate the role of CD45 in lymphocyte development, activation, and anergy.
• Quality Control Reagent: Acts as a control material in the manufacturing and batch release testing of CD45-targeting therapeutic proteins or diagnostic kits.

Basic Information

Item	Detail
Product Name	Leukocyte Common Antigen-Related Peptide
CAS No.	134549-71-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CD45-Related Peptide; LCA Peptide; Protein Tyrosine Phosphatase, Receptor Type C (PTPRC) Peptide; T200 Glycoprotein Peptide; Leukocyte Common Antigen Peptide; Ly-5 Peptide (Mouse Homolog); CD45 Antigen-Related Sequence; LCA Receptor Peptide
EINECS	Contact for details

Quality Control

Our Leukocyte Common Antigen-Related Peptide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide comprehensive Certificates of Analysis (COA) with detailed chromatograms and analytical data upon request, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.