Description

Polycomb Protein, Insect is a highly purified recombinant protein derived from insect cell expression systems, specifically designed for research applications. This product is critical for studying epigenetic regulation, chromatin remodeling, and gene silencing mechanisms in developmental biology and disease models. It is an essential reagent for molecular biologists, biochemists, and pharmaceutical researchers focused on epigenetics and targeted therapeutic development.

Application

• Epigenetic Research: Used in chromatin immunoprecipitation (ChIP) assays, co-immunoprecipitation (Co-IP), and other studies to investigate Polycomb-mediated gene repression.
• Biochemical Assay Development: Serves as a key component in enzymatic activity assays (e.g., histone methyltransferase assays) and protein-protein interaction studies.
• Antibody Validation & Specificity Testing: Acts as a positive control and antigen for validating antibodies targeting Polycomb group (PcG) proteins.
• Cell Signaling Pathway Analysis: Employed in research focused on understanding the role of Polycomb complexes in stem cell pluripotency, differentiation, and cancer progression.
• Drug Discovery & Screening: Utilized in high-throughput screening platforms to identify and characterize small molecule inhibitors or modulators of Polycomb complex activity.
• Protein Standard & Reference Material: Provides a defined standard for quantitative Western blotting, mass spectrometry, and other proteomic analyses.

Basic Information

Product Name	Polycomb Protein, Insect
CAS No.	134549-01-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Recombinant Insect Polycomb Protein; PcG Protein (Insect); Polycomb Group Protein; Chromobox Protein Homolog; CBX Protein (Insect); Histone Methyltransferase Complex Component; PRC1 Component; Epigenetic Regulatory Protein
EINECS	Contact for details

Quality Control

Our Polycomb Protein, Insect is produced under stringent conditions to ensure high purity, activity, and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including SDS-PAGE, Western blot analysis, and functional activity assays. A detailed Certificate of Analysis (COA) documenting purity, concentration, biological activity, and endotoxin levels is provided with every shipment to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Clear or slightly opalescent solution
Purity (SDS-PAGE)	≥ 90%
Protein Concentration	≥ 0.5 mg/mL
Biological Activity	Confirmed by functional assay
Endotoxin Level	< 1.0 EU/µg
Buffer Composition	Specified in COA
Identification (Western Blot)	Positive for target protein

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.