Description

(R)-(+)-2-Diphenylphosphino-2'-Methoxy-1,1'-Binaphthyl CAS NO 134484-37-0 is a high-value, chiral monophosphine ligand belonging to the MOP (Methoxy-substituted) family. This compound matters significantly as a privileged ligand in asymmetric catalysis, enabling the synthesis of enantiomerically pure pharmaceuticals and fine chemicals with high selectivity and yield. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control in transition metal-catalyzed reactions such as hydrogenations and cross-couplings.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral intermediates for active pharmaceutical ingredients (APIs).
• Cross-Coupling Reactions: Employed in palladium-catalyzed asymmetric Suzuki-Miyaura and Heck reactions to construct chiral biaryl frameworks.
• Pharmaceutical Intermediate Synthesis: Critical for the production of enantiomerically pure compounds used in drug discovery and development.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and pesticides with improved efficacy and environmental profile.
• Academic & Industrial R&D: A valuable tool for methodology development in organic synthesis and catalysis research.
• Fine Chemical Production: Facilitates the manufacture of specialty flavors, fragrances, and advanced materials requiring specific chirality.

Basic Information

Product Name	(R)-(+)-2-Diphenylphosphino-2'-Methoxy-1,1'-Binaphthyl
CAS No.	134484-37-0
Molecular Formula	C33H25OP
Molecular Weight	468.52 g/mol
Synonyms	(R)-(+)-2-(Diphenylphosphino)-2'-methoxy-1,1'-binaphthyl; (R)-2-(Diphenylphosphino)-2'-methoxy-1,1'-binaphthyl; (R)-MOP; (R)-2-Methoxy-2'-(diphenylphosphino)-1,1'-binaphthyl; (R)-2'-Methoxy-2-(diphenylphosphino)-1,1'-binaphthyl; (R)-(+)-MOP; (R)-MeO-MOP; Ligand MOP
EINECS	Contact for details

Quality Control

Our (R)-(+)-2-Diphenylphosphino-2'-Methoxy-1,1'-Binaphthyl is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) with detailed chromatographic data, including enantiomeric excess (ee), are provided to guarantee reproducible performance in your catalytic applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the container to reach room temperature in a dry environment before opening to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.