Description

2,3-Difluoroanisole is a versatile fluorinated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the development of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving charge transport and device performance.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, chemical resistance, and surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a protecting group precursor in multi-step synthetic routes.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and material science research in academic and industrial R&D laboratories.

Basic Information

Product Name	2,3-Difluoroanisole
CAS No.	134364-69-5
Molecular Formula	C7H6F2O
Molecular Weight	144.12 g/mol
Synonyms	1,2-Difluoro-3-methoxybenzene; 3-Methoxy-1,2-difluorobenzene; 2,3-Difluorophenyl methyl ether; Anisole, 2,3-difluoro-; Difluoroanisole; 2,3-DFA
EINECS	Contact for details

Quality Control

Our 2,3-Difluoroanisole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total
Density (20°C)	~1.25 g/cm³
Refractive Index (n20D)	~1.47

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.