Description

Ace2 Protein is a purified recombinant protein that serves as a critical enzyme and receptor in various physiological and research contexts. Its primary value lies in its high purity and biological activity, making it an essential reagent for advanced life science research and diagnostic development. This product is indispensable for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic industries, particularly those focused on cardiovascular, renal, and infectious disease research.

Application

• Biochemical Research: Used as a key enzyme (angiotensin-converting enzyme 2) in studies of the renin-angiotensin system (RAS) and its role in blood pressure regulation and fluid balance.
• Drug Discovery & Screening: Employed in high-throughput screening (HTS) assays to identify and characterize potential inhibitors or modulators of ACE2 activity for therapeutic development.
• Diagnostic Kit Development: Serves as a critical antigen or capture reagent in the development of immunoassays and biosensors for detecting related biomarkers or antibodies.
• Virology & Infectious Disease Research: Utilized in studies investigating viral entry mechanisms, particularly as a functional receptor for certain coronaviruses, to understand pathogenesis and develop intervention strategies.
• Protein-Protein Interaction Studies: Acts as a target protein in surface plasmon resonance (SPR), isothermal titration calorimetry (ITC), or pull-down assays to map binding partners and signaling pathways.
• Cell Culture & Functional Assays: Added to cell culture systems to study its enzymatic function or receptor activity in modulating cellular responses in vitro.

Basic Information

Product Name	Ace2 Protein
CAS No.	134324-48-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Angiotensin-Converting Enzyme 2; ACE2; ACEH; Angiotensin-Converting Enzyme Homolog; ACE-Related Carboxypeptidase; Metalloprotease ACE2; hACE2; Recombinant Human ACE2 Protein; UNII-MDP2567W5O
EINECS	Contact for details

Quality Control

Our Ace2 Protein is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes rigorous quality testing, including purity analysis by SDS-PAGE and HPLC, assessment of enzymatic activity, and endotoxin level testing. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or clear solution
Purity (SDS-PAGE)	> 95%
Identification (Western Blot)	Positive
Biological Activity (Enzymatic Assay)	Contact for details
Endotoxin Level (LAL Test)	< 1.0 EU/µg
Protein Concentration	Contact for details
Buffer Composition	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.