Description

Nk-1 Protein CAS NO 134089-00-2 is a high-purity, biologically active protein used in advanced research and development. This compound is critical for studying neurokinin-1 (NK-1) receptor pathways, which are involved in a wide range of physiological processes. It is an essential reagent for pharmaceutical discovery, biochemical research, and diagnostic assay development, providing researchers with a reliable and consistent tool for their work.

Application

• Pharmaceutical R&D: Used as a key reagent in the discovery and development of novel therapeutics targeting the NK-1 receptor for conditions like emesis, depression, and pain.
• Biochemical Research: Serves as a standard or ligand in receptor binding assays, signal transduction studies, and functional characterization of the NK-1 receptor.
• Diagnostic Development: Employed in the development of immunoassays and other diagnostic tests to detect or quantify receptor activity or related biomarkers.
• Cell Biology Studies: Utilized to investigate the role of substance P and NK-1 receptor interactions in inflammation, cell proliferation, and neuronal communication.
• Academic Research: A fundamental tool for universities and research institutes studying neuropeptides, G-protein coupled receptors (GPCRs), and central nervous system function.

Basic Information

Item	Detail
Product Name	Nk-1 Protein
CAS No.	134089-00-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Neurokinin-1 Protein; NK-1 Receptor Protein; Substance P Receptor Protein; TACR1 Protein; NK1R; SPR; Neurokinin 1 Receptor; Tachykinin Receptor 1
EINECS	Contact for details

Quality Control

Our Nk-1 Protein is produced under stringent conditions to ensure high biological activity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques, including HPLC for purity and functional assays for activity confirmation. A Certificate of Analysis (COA) detailing purity, potency, and endotoxin levels is provided with each batch to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture condensation. Aliquot reconstituted protein to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Biological Activity (Cell-based assay)	Fully active
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.