Description

Hemoglobin F Brooklyn CAS NO 134011-43-1 is a specific variant of fetal hemoglobin, a critical oxygen-transporting protein. This compound is of significant interest for advanced biochemical research and diagnostic development due to its unique structural and functional properties. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical developers working in hematology, genetic disorders, and novel therapeutic modalities.

Application

• Biochemical Research: Used as a standard or reagent in studies investigating hemoglobin structure-function relationships, oxygen affinity, and allosteric regulation.
• Diagnostic Development: Serves as a critical component in the calibration and validation of diagnostic assays for hemoglobinopathies, such as sickle cell disease and thalassemia.
• Pharmaceutical R&D: Employed in research programs focused on developing treatments for blood disorders, including gene therapy and drug screening platforms.
• Clinical Reference Material: Acts as a high-purity reference material in clinical laboratories for quality control and method verification of hemoglobin analysis techniques like HPLC or electrophoresis.
• Educational & Training Kits: Incorporated into advanced educational kits for university-level biochemistry and medical technology courses.

Basic Information

Product Name	Hemoglobin F Brooklyn
CAS No.	134011-43-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb F Brooklyn; Fetal Hemoglobin Brooklyn; Hemoglobin F (Brooklyn variant); γ-Globin Brooklyn variant; HbF (Brooklyn); Fetal Hb Brooklyn; Hemoglobin F Mutant Brooklyn
EINECS	Contact for details

Quality Control

Our Hemoglobin F Brooklyn is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and purity for research applications. Each lot is characterized using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and relevant biological activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain integrity. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC/Electrophoresis)	Conforms to standard for Hb F Brooklyn
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Solubility	Clear solution in appropriate buffer
Biological Activity (Oxygen Binding)	Contact for details
Endotoxin Level (LAL)	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.