Description

1-Azabicyclo[3.1.1]heptane-5-carboxamide (9Ci) is a specialized bicyclic amide compound with a unique bridged nitrogen-containing structure. This high-purity intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Organic Synthesis Research: Serves as a versatile scaffold for constructing novel nitrogen-containing heterocycles in academic and industrial R&D settings.
• Agrochemical Development: Used in the research phase for creating new pesticides or herbicides with specific biological activity.
• Ligand and Catalyst Preparation: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Chemical Biology Probe Synthesis: Employed in the development of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1-Azabicyclo[3.1.1]heptane-5-carboxamide (9Ci)
CAS No.	133998-48-8
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	1-Azabicyclo[3.1.1]heptane-5-carboxamide; 5-Carbamoyl-1-azabicyclo[3.1.1]heptane; 1-Azabicyclo[3.1.1]heptane-5-carboxylic acid amide; Bicyclo[3.1.1]heptane-5-carboxamide, 1-aza-; 133998-48-8; 5-Carboxamido-1-azabicyclo[3.1.1]heptane
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[3.1.1]heptane-5-carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.