Description

Bicyclohexyl]-4-Yl]-4-(Trifluoromethoxy)- CAS NO 133914-49-5 is a high-purity, advanced organic intermediate characterized by its bicyclic structure and trifluoromethoxy functional group. This compound matters for its role as a critical building block in the synthesis of complex molecules, offering unique steric and electronic properties that are difficult to achieve with simpler analogs. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients, particularly where enhanced metabolic stability and lipophilicity are desired targets.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders or requiring specific pharmacokinetic profiles.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group can contribute to improved biological activity and environmental persistence.
• Liquid Crystal Materials: Acts as a potential component or precursor in the synthesis of specialty chemicals for electronic displays, leveraging its rigid bicyclic core.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a building block for electron-transport or host materials in OLED devices due to its molecular architecture.
• Advanced Material Research: Employed in academic and industrial labs for developing novel polymers, ligands for catalysis, or other functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	Bicyclohexyl]-4-Yl]-4-(Trifluoromethoxy)-
CAS No.	133914-49-5
Molecular Formula	C19H25F3O
Molecular Weight	326.40 g/mol
Synonyms	4-(Trifluoromethoxy)-[1,1'-bicyclohexyl]-4-carbonitrile (common misnomer); 4'-(Trifluoromethoxy)[1,1'-bicyclohexyl]-4-carbonitrile; 4-Cyano-4'-(trifluoromethoxy)bicyclohexyl; Bicyclohexyl-4-carbonitrile, 4'-(trifluoromethoxy)-; [1,1'-Bicyclohexyl]-4-carbonitrile, 4'-(trifluoromethoxy)-; 4-(Trifluoromethoxy)-[1,1'-bicyclohexyl]-4-yl cyanide; 4-Cyano-4'-(trifluoromethoxy)-1,1'-bicyclohexyl
EINECS	Contact for details

Quality Control

Every batch of Bicyclohexyl]-4-Yl]-4-(Trifluoromethoxy)- is produced and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We can support development projects with analytical method development and validation data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.