Description

n-Boc-D-Cysteine Methyl Ester is a protected, non-natural amino acid derivative essential for advanced peptide synthesis. This high-purity chiral building block is critical for researchers and manufacturers requiring precise stereochemical control in the development of novel pharmaceuticals and bioactive compounds. It is primarily utilized in the synthesis of peptide-based drugs, enzyme inhibitors, and other complex biomolecules within the pharmaceutical, biotechnology, and life science research sectors.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide-based active pharmaceutical ingredients (APIs) and prodrugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-cysteine residues with Boc (tert-butoxycarbonyl) side-chain protection.
• Bioconjugation & Linker Chemistry: Serves as a precursor for creating thiol-reactive crosslinkers or for introducing protected thiol groups into biomolecules.
• Protease Inhibitor Development: A valuable building block in the research and development of cysteine protease inhibitors.
• Chemical Biology Research: Employed in the study of protein structure-function relationships and the design of synthetic peptides with modified properties.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective organic synthesis.

Basic Information

Product Name	n-Boc-D-Cysteine Methyl Ester
CAS No.	133904-67-3
Molecular Formula	C9H17NO4S
Molecular Weight	235.30 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-3-mercaptopropanoic acid methyl ester; D-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; Methyl (R)-2-((tert-butoxycarbonyl)amino)-3-sulfanylpropanoate; Boc-D-Cys-OMe; Boc-D-Cysteine methyl ester; (R)-Methyl 2-((tert-butoxycarbonyl)amino)-3-mercaptopropanoate; tert-Butoxycarbonyl-D-cysteine methyl ester
EINECS	Contact for details

Quality Control

Our n-Boc-D-Cysteine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool, and well-ventilated place. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or ambient conditions should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.