Description

Cyclopropane, 2-(1-Butenyl)-3-Ethyl-1,1-Difluoro-, [2Alpha(Z),3Alpha]- (9Ci) is a specialized fluorinated cyclopropane derivative with a defined stereochemistry. This compound is valued as a key advanced pharmaceutical intermediate (API intermediate) and a versatile building block in synthetic organic chemistry. It is primarily needed by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used as a building block for developing new-generation pesticides and herbicides with enhanced activity and environmental profile.
• Material Science: Acts as a monomer or modifier in the creation of specialty polymers with unique fluorinated properties, such as chemical resistance or low surface energy.
• Organic Synthesis: Employed in advanced organic reactions, including cycloadditions and cross-coupling, to construct complex, stereodefined molecular architectures.
• Ligand & Catalyst Development: Utilized in the design of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable compound for studying the effects of fluorine substitution and cyclopropane ring strain on chemical reactivity and biological activity.

Basic Information

Item	Details
Product Name	Cyclopropane, 2-(1-Butenyl)-3-Ethyl-1,1-Difluoro-, [2Alpha(Z),3Alpha]- (9Ci)
CAS No.	133895-54-2
Molecular Formula	C11H18F2
Molecular Weight	188.26 g/mol
Synonyms	(Z)-2-(1-Butenyl)-3-ethyl-1,1-difluorocyclopropane; [2α(Z),3α]-2-(1-Butenyl)-3-ethyl-1,1-difluorocyclopropane; 1,1-Difluoro-2-[(1Z)-1-buten-1-yl]-3-ethylcyclopropane; Difluorocyclopropane derivative (C11H18F2); Fluorinated cyclopropane building block; (Z)-configured fluorocyclopropane
EINECS	Contact for details

Quality Control

Our production of Cyclopropane, 2-(1-Butenyl)-3-Ethyl-1,1-Difluoro-, [2Alpha(Z),3Alpha]- (9Ci) adheres to stringent quality protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation and stereochemical integrity, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term stability, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C. The compound is moisture-sensitive and should be handled in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Isomeric Purity (Z-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.