Description

1-Thio-α-Tocopherol is a sulfur-containing derivative of vitamin E (α-tocopherol), known for its enhanced antioxidant properties and stability. This compound is valued for its ability to protect sensitive ingredients from oxidative degradation, thereby extending shelf life and maintaining product efficacy. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and high-performance cosmetic industries seeking advanced stabilization solutions.

Application

• As a potent antioxidant and stabilizer in pharmaceutical formulations, including injectables and oral dosage forms.
• Key ingredient in anti-aging and protective skincare products, such as serums and creams, to combat free radical damage.
• Used in dietary supplements and nutraceuticals to enhance the oxidative stability of sensitive active ingredients like ω-3 fatty acids.
• Stabilizing agent in functional foods and beverages prone to oxidation.
• Application in animal feed and veterinary products to improve the stability of fat-soluble vitamins.
• Research and development of novel drug delivery systems and advanced material science applications.

Basic Information

Product Name	1-Thio-α-Tocopherol
CAS No.	133869-30-4
Molecular Formula	C29H50O2S
Molecular Weight	462.77 g/mol
Synonyms	1-Thio-α-Tocopherol; α-Tocopherol 1-sulfide; Vitamin E thioether; 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-1-thiochroman-6-ol; 6-Hydroxy-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-1-thiochroman; D-α-Tocopherol 1-sulfide
EINECS	Contact for details

Quality Control

Our 1-Thio-α-Tocopherol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for pharmaceutical and nutraceutical applications. A comprehensive Certificate of Analysis (COA) documenting purity, related substances, and residual solvents is available upon request, supporting compliance with cGMP and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) in a cool, dry place at 2-8°C for long-term stability. This product is easily oxidized and light-sensitive; prolonged exposure to air, heat, or light should be avoided to maintain potency.

Specification

Item	Specification
Appearance	Pale yellow to yellow viscous liquid or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.