Description

5-Oxo-1-p-Tolyl-Pyrrolidine-3-Carboxylic Acid is a high-purity pyrrolidine derivative, a crucial advanced pharmaceutical intermediate and building block in organic synthesis. Its value lies in its role as a key precursor for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research. This compound is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric applications.
• API Synthesis: Used as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Agrochemical Research: Serves as a key intermediate in the development of new pesticides and herbicides with specific biological activity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, ligands, and catalysts for asymmetric synthesis.
• Academic & R&D: A valuable compound for medicinal chemistry research, structure-activity relationship (SAR) studies, and library synthesis in academic and industrial laboratories.
• Peptidomimetics: Used in the design and synthesis of peptidomimetic compounds, which mimic the function of natural peptides.

Basic Information

Product Name	5-Oxo-1-p-Tolyl-Pyrrolidine-3-Carboxylic Acid
CAS No.	133747-57-6
Molecular Formula	C13H15NO3
Molecular Weight	233.26 g/mol
Synonyms	1-(4-Methylphenyl)-5-oxopyrrolidine-3-carboxylic acid; 5-Oxo-1-(p-tolyl)pyrrolidine-3-carboxylic acid; 1-p-Tolyl-5-oxopyrrolidine-3-carboxylic acid; 3-Carboxy-1-(4-methylphenyl)-2-pyrrolidinone; 5-Oxo-1-(4-methylphenyl)-3-pyrrolidinecarboxylic acid; Pyrrolidine-3-carboxylic acid, 5-oxo-1-(4-methylphenyl)-; 133747-57-6 (CAS).
EINECS	Contact for details

Quality Control

Our 5-Oxo-1-p-Tolyl-Pyrrolidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.