Description

Des-Phenylalanine-Anantin is a high-purity, synthetic peptide derivative of the naturally occurring sweet-tasting protein, anantin. This compound is engineered for advanced research and development applications, offering a modified structure that excludes phenylalanine for specific biochemical studies. It serves as a critical tool for scientists investigating taste receptor mechanisms, protein engineering, and the development of novel flavor modulators or low-calorie sweetener candidates. Key target industries include pharmaceutical research, food science, and biotechnology, where precise molecular tools are essential for innovation.

Application

• Biochemical Research: Used as a reference standard and active compound in studies of sweet taste receptors (T1R2/T1R3) and signal transduction pathways.
• Flavor Science & Food Technology: Investigated for its potential as a high-potency sweetener or flavor enhancer in the development of reduced-sugar products.
• Pharmaceutical Development: Serves as a lead compound or molecular scaffold in drug discovery programs targeting metabolic disorders or taste-related conditions.
• Protein Engineering: Acts as a model peptide for studying structure-activity relationships (SAR) and designing novel bioactive peptides.
• Diagnostic Reagents: Potential use in the formulation of assays and kits for taste receptor analysis and screening.
• Academic Research: Employed in university and institutional labs for fundamental research in biochemistry, sensory biology, and molecular biology.

Basic Information

Product Name	Des-Phenylalanine-Anantin
CAS No.	133658-46-5
Molecular Formula	C164H246N44O49S2
Molecular Weight	~3670.1 g/mol
Synonyms	Des-Phe-Anantin; Anantin (Des-Phenylalanine); De-Phe-Anantin; Anantin derivative; Sweet-tasting protein analog; T1R2/T1R3 receptor ligand; [Des-Phe]Anantin; Modified anantin peptide
EINECS	Contact for details

Quality Control

Our Des-Phenylalanine-Anantin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by AAA)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.