Description

Fmoc-Ile-Ol CAS NO 133565-46-5 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block, enabling the controlled elongation of peptide chains while preventing unwanted side reactions. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and CROs engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Fmoc-protected amino alcohol for the sequential assembly of peptides on resin.
• Therapeutic Peptide Development: Used in the research and production of peptide-based pharmaceuticals targeting various diseases.
• Peptidomimetic Design: Incorporation into non-natural peptide analogs to enhance metabolic stability and bioavailability.
• Bioconjugation and Labeling: Serves as a versatile intermediate for attaching peptides to other molecules, surfaces, or fluorescent tags.
• Combinatorial Chemistry Libraries: A key component in generating diverse arrays of compounds for high-throughput screening in drug discovery.
• Academic and Industrial Research: Essential reagent for biochemical studies involving protein-protein interactions and signal transduction pathways.

Basic Information

Product Name	Fmoc-Ile-Ol
CAS No.	133565-46-5
Molecular Formula	C20H23NO3
Molecular Weight	325.40 g/mol
Synonyms	Fmoc-Ile-ol; N-(9-Fluorenylmethoxycarbonyl)-L-isoleucinol; (2S,3S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-methylpentan-1-ol; Fmoc-L-isoleucinol; Nα-Fmoc-L-isoleucinol; Fmoc-Ile-ol-OH (deprecated); N-Fmoc-isoleucinol; Fmoc-Isoleucinol
EINECS	Contact for details

Quality Control

Every batch of Fmoc-Ile-Ol is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing results from HPLC, NMR, and other relevant analyses to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.