Description

Glycine, n-[(1,1-Dimethylethoxy)Carbonyl]Glycyl-n-Methyl- is a specialized Boc-protected dipeptide derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in providing a protected amino acid sequence, enabling precise and controlled peptide chain elongation while preventing unwanted side reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel therapeutic peptides and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase and solution-phase synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Peptide Research: Used in academic and industrial R&D for constructing custom peptide sequences for drug discovery and biological studies.
• Bioconjugation: Employed in the synthesis of peptide tags and linkers for protein engineering and antibody-drug conjugate (ADC) development.
• Combinatorial Chemistry: Serves as a building block in libraries for high-throughput screening to identify new bioactive compounds.
• Process Development: Used in scaling up synthetic routes for peptide therapeutics, ensuring reproducibility and quality.

Basic Information

Product Name	Glycine, n-[(1,1-Dimethylethoxy)Carbonyl]Glycyl-n-Methyl-
CAS No.	133498-97-2
Molecular Formula	C10H18N2O5
Molecular Weight	246.26 g/mol
Synonyms	Boc-Gly-Gly-NHMe; Boc-Gly-Gly-N-methylamide; N-(tert-Butoxycarbonyl)glycylglycine N-methylamide; Nα-Boc-Glycyl-N-methylglycine; (tert-Butoxycarbonyl)glycylglycine methylamide; Glycine, N-[(1,1-dimethylethoxy)carbonyl]glycyl-N-methyl-; Boc-Gly-Gly-NHCH3; 2-[[(2-Methylamino-2-oxoethyl)amino]-N-(tert-butoxycarbonyl)acetamide
EINECS	Contact for details

Quality Control

Our Glycine, n-[(1,1-Dimethylethoxy)Carbonyl]Glycyl-n-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.