Description

Gp130 Signal Transducer CAS NO 133483-10-0 is a high-purity chemical reference standard and research compound. This product is critical for advancing studies in cellular signaling pathways, particularly those involving interleukin-6 (IL-6) family cytokines. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for target validation, assay development, and mechanistic studies in immunology, oncology, and inflammatory disease research.

Application

• Biochemical Research: Used as a key reference standard in studies of the JAK/STAT signaling pathway.
• Drug Discovery & Development: Essential for high-throughput screening (HTS) assays to identify and validate novel therapeutic agents targeting gp130-mediated signaling.
• Cell Signaling Studies: Employed in mechanistic investigations of cytokine receptor complexes and downstream signal transduction events.
• Academic Research: A vital tool in university and institutional labs for fundamental research in immunology, cancer biology, and autoimmune disorders.
• Diagnostic Development: Serves as a critical component in the development of ELISA and other immunoassays designed to detect or quantify gp130-related biomarkers.
• Pharmaceutical QC: Can be used as a system suitability standard in quality control processes for biologics targeting the IL-6/gp130 axis.

Basic Information

Product Name	Gp130 Signal Transducer
CAS No.	133483-10-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	gp130; CD130; IL6ST; Interleukin-6 receptor subunit beta; IL-6R-beta; IL-6 receptor beta subunit; Membrane glycoprotein 130; Oncostatin M receptor; OSMR; Signal transducer gp130
EINECS	Contact for details

Quality Control

Our Gp130 Signal Transducer is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including purity assessment by HPLC and identity confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. The product should be handled in accordance with good laboratory practice.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Biological Activity	Assay-dependent; Data available on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.