Description

Boc-D-Glu(Ochex)-Oh is a protected amino acid derivative, specifically a Boc-protected D-glutamic acid with a cyclohexyl ester side chain. This compound is a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic tools, and advanced biochemical research.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the solid-phase and solution-phase synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Development: Used in the preparation of labeled peptides and molecular probes for biochemical assays, imaging, and diagnostic applications.
• Peptidomimetic Research: Essential for constructing non-natural peptide analogs to study structure-activity relationships (SAR) and enhance metabolic stability.
• Catalyst & Ligand Synthesis: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & R&D: Employed in university and industrial research laboratories for exploring new synthetic methodologies and bioactive compounds.

Basic Information

Product Name	Boc-D-Glu(Ochex)-Oh
CAS No.	133464-27-4
Molecular Formula	C₁₆H₂₇NO₆
Molecular Weight	329.39 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-glutamic acid 1-cyclohexyl ester; Boc-D-glutamic acid 1-cyclohexyl ester; (R)-2-((tert-Butoxycarbonyl)amino)pentanedioic acid 5-cyclohexyl ester; Boc-D-Glu(OcHex)-OH; Boc-D-Glu(Ochex)-OH; Boc-D-Glu(OcHx)-OH
EINECS	Contact for details

Quality Control

Our Boc-D-Glu(Ochex)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure the material meets the stringent requirements for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.