Description

Iloperidone is a high-purity pharmaceutical active ingredient, a second-generation atypical antipsychotic used in the treatment of schizophrenia. Its primary value lies in its distinct receptor binding profile, which offers a balance of efficacy and a potentially favorable tolerability profile for patients. This compound is essential for pharmaceutical manufacturers and research institutions engaged in the development and production of neuropsychiatric medications, as well as for analytical and quality control laboratories requiring reference standards.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the formulation of finished dosage forms for the treatment of schizophrenia.
• Pharmaceutical Research & Development: Serves as a key reference compound in preclinical and clinical studies for novel antipsychotic therapies.
• Analytical Standard: Used as a certified reference material (CRM) in HPLC, LC-MS, and other analytical methods for quality control and method validation.
• Generic Drug Manufacturing: Critical raw material for companies producing generic versions of iloperidone-based medications.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research to understand drug behavior in biological systems.

Basic Information

Product Name	Iloperidone
CAS No.	133454-47-4
Molecular Formula	C24H27FN2O4
Molecular Weight	426.48 g/mol
Synonyms	Fanapt; Zomaril; HP 873; 4'-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)piperidino]propoxy]-3'-methoxyacetophenone; 1-[4-[3-[4-(6-Fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy]-3-methoxyphenyl]ethanone; (RS)-1-[4-[3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]ethanone
EINECS	Contact for details

Quality Control

Our Iloperidone is manufactured under strict quality management systems, ensuring it meets the rigorous standards required for pharmaceutical applications. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles, using validated analytical methods such as HPLC and NMR. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.