Description

Mitochondrial Import Receptor Subunit Tom40, S Cerevisiae is a critical protein component of the Translocase of the Outer Membrane (TOM) complex in yeast, essential for the import of nuclear-encoded proteins into mitochondria. This highly specific reagent is vital for fundamental research into mitochondrial biogenesis, protein trafficking, and cellular energetics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on molecular biology, biochemistry, and studies of mitochondrial dysfunction.

Application

• Biochemical Research: A key reagent for in vitro reconstitution assays to study the mechanisms of the mitochondrial protein import machinery.
• Structural Biology: Used in X-ray crystallography and cryo-electron microscopy studies to determine the architecture of the TOM complex.
• Drug Discovery Screening: Serves as a target protein in assays designed to identify compounds that modulate mitochondrial import, relevant for metabolic and neurodegenerative diseases.
• Functional Proteomics: Employed in pull-down and co-immunoprecipitation experiments to identify interacting partner proteins and map the mitochondrial import network.
• Educational Kits: A component in advanced university-level teaching kits for practical courses on molecular cell biology and organelle function.

Basic Information

Product Name	Mitochondrial Import Receptor Subunit Tom40, S Cerevisiae
CAS No.	133424-34-7
Molecular Formula	Contact for details
Molecular Weight	~40 kDa (Contact for exact lot-specific data)
Synonyms	TOM40 Yeast
Mitochondrial import receptor subunit TOM40
Translocase of outer membrane 40 kDa subunit
Yeast Tom40 protein
Saccharomyces cerevisiae Tom40
Outer membrane protein import receptor
Mitochondrial precursor proteins import receptor
EINECS	Contact for details

Quality Control

Our Mitochondrial Import Receptor Subunit Tom40, S Cerevisiae is produced and handled under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot is subjected to rigorous purity analysis, including SDS-PAGE and Western Blot confirmation. We provide comprehensive Certificates of Analysis (COA) detailing purity, concentration, buffer composition, and functional activity data upon request, supporting compliance with rigorous research standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at ≤ -20°C in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed properly after use. Store away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Clear to slightly opalescent solution
Identification (SDS-PAGE/Western Blot)	Complies
Purity (SDS-PAGE)	≥ 90%
Protein Concentration	Provided on COA (typically 0.1 - 1.0 mg/mL)
Buffer Composition	Tris-HCl, NaCl, Glycerol, DTT (exact concentrations on COA)
Biological Activity (Functional Assay)	Contact for details
Endotoxin Level	< 1.0 EU/µg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.