Description

1-Pyrrolidinecarboxamide,n-Hydroxy-2,5-Dimethyl-,(2R-Trans)-(9Ci) is a high-purity chiral compound belonging to the class of pyrrolidine-based hydroxamic acid derivatives. This specialized chemical serves as a critical building block and intermediate in advanced organic synthesis, particularly for the development of novel pharmaceutical agents and bioactive molecules. It is essential for research and production in medicinal chemistry, where its stereochemistry and functional groups enable the creation of targeted, high-value compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for enzyme inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for various therapeutic targets.
• Biochemical Tool Compound: Acts as a potential ligand or probe in biochemical assays to study enzyme function and signal transduction pathways.
• Organic Synthesis Building Block: Employed in the synthesis of complex natural product analogs and other fine chemicals requiring a defined stereocenter.
• Agrochemical Development: Investigated as an intermediate for creating novel, high-performance crop protection agents.

Basic Information

Item	Details
Product Name	1-Pyrrolidinecarboxamide,n-Hydroxy-2,5-Dimethyl-,(2R-Trans)-(9Ci)
CAS No.	133378-82-2
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	(2R,5R)-N-Hydroxy-2,5-dimethylpyrrolidine-1-carboxamide; (2R-trans)-N-Hydroxy-2,5-dimethyl-1-pyrrolidinecarboxamide; trans-N-Hydroxy-2,5-dimethylpyrrolidine-1-carboxamide; (2R,5R)-2,5-Dimethyl-N-hydroxypyrrolidine-1-carboxamide; 1-Pyrrolidinecarboxamide, N-hydroxy-2,5-dimethyl-, (2R,5R)-; A chiral hydroxamic acid derivative
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxamide,n-Hydroxy-2,5-Dimethyl-,(2R-Trans)-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry, to confirm identity, enantiomeric excess, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.