Description

1-Azabicyclo[2.2.1]heptane-3-carbonitrile, endo-(9CI) is a high-value, bicyclic nitrile building block with a constrained, bridged structure. This compound is prized for its role as a versatile chiral intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific stereochemical requirements.
• Catalyst & Ligand Development: Serves as a precursor for creating novel chiral catalysts and ligands used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and the exploration of new chemical spaces.

Basic Information

Product Name	1-Azabicyclo[2.2.1]heptane-3-carbonitrile, endo-(9CI)
CAS No.	133366-32-2
Molecular Formula	C7H10N2
Molecular Weight	122.17 g/mol
Synonyms	endo-2-Azabicyclo[2.2.1]heptane-3-carbonitrile; 3-Cyano-2-azabicyclo[2.2.1]heptane, endo-; 2-Azabicyclo[2.2.1]heptane-3-carbonitrile, endo-; endo-3-Cyano-2-azabicyclo[2.2.1]heptane; Bicyclo[2.2.1]heptane-3-carbonitrile, 1-aza-, endo-; (1R,2S,4S)-2-Azabicyclo[2.2.1]heptane-3-carbonitrile; (1S,2R,4R)-2-Azabicyclo[2.2.1]heptane-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.1]heptane-3-carbonitrile, endo-(9CI) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or GC), chiral purity, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (endo-isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.