Description

Stem Cell Factor, Human CAS NO 133352-98-4 is a critical hematopoietic cytokine essential for the survival, proliferation, and differentiation of stem and progenitor cells. This high-purity recombinant protein is vital for advanced life science research and therapeutic development, ensuring reliable and reproducible biological activity. It is primarily utilized by biotechnology firms, pharmaceutical R&D departments, and academic research institutions focused on hematopoiesis, stem cell biology, and regenerative medicine.

Application

• Ex Vivo Stem Cell Expansion: Crucial for culturing and amplifying hematopoietic stem cells (HSCs) and other progenitor cells in bioreactors.
• Cell Therapy & Regenerative Medicine: A key component in media formulations for generating cell-based therapies and tissue engineering constructs.
• Hematopoiesis Research: Used to study the mechanisms of blood cell formation, lineage commitment, and bone marrow microenvironment interactions.
• Drug Discovery & Screening: Employed in assays to identify compounds that modulate stem cell factor receptor (c-Kit) signaling pathways.
• Diagnostic Development: Serves as a standard or reagent in the development of immunoassays and diagnostic kits related to hematopoietic disorders.
• Coculture Systems: Supports the growth of mast cells and other c-Kit expressing cell types in specialized coculture research models.

Basic Information

Product Name	Stem Cell Factor, Human
CAS No.	133352-98-4
Molecular Formula	C845H1343N229O255S9
Molecular Weight	Approx. 18.5 kDa (non-glycosylated)
Synonyms	SCF; Kit Ligand; KL; Steel Factor; SF; Mast Cell Growth Factor; MGF; c-Kit Ligand; Stem Cell Factor (245 aa); rhSCF; Recombinant Human Stem Cell Factor
EINECS	Contact for details

Quality Control

Our Stem Cell Factor, Human is manufactured under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is subjected to a comprehensive battery of tests including identity confirmation, purity analysis, endotoxin level determination, and functional bioactivity assays. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee consistency and reliability for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -20°C to -80°C to prevent repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the vial is at room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Single band corresponding to ~18-20 kDa
Purity (HPLC)	≥ 95%
Biological Activity (Cell Proliferation Assay)	ED50 ≤ 5.0 ng/mL
Endotoxin (LAL)	< 1.0 EU/μg
Protein Content (UV Spectroscopy)	≥ 80% of label claim
Solubility	Soluble in water or PBS

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.