Description

Ioversol is a non-ionic, water-soluble, tri-iodinated contrast agent belonging to the class of low-osmolar radiographic media. Its primary value lies in its excellent safety profile and high radiopacity, making it a preferred agent for enhancing vascular and tissue visualization in diagnostic imaging. This compound is essential for manufacturers in the pharmaceutical and medical device industries, particularly for formulating injectable solutions used in computed tomography (CT), angiography, and urography procedures.

Application

• Diagnostic Imaging Contrast Media: Primary component in formulations for intravascular injection in CT scans (body and neurological).
• Angiographic Procedures: Used in coronary, cerebral, and peripheral angiography to visualize blood vessels and detect blockages.
• Urography and Pyelography: Employed for radiographic examination of the kidneys, ureters, and bladder.
• Myelography: For imaging of the spinal canal and subarachnoid space (using specific approved formulations).
• Arthrography: Used in joint imaging to assess cartilage, ligaments, and joint capsules.
• Pharmaceutical Intermediates: Serves as a key active pharmaceutical ingredient (API) in the production of finished contrast agent solutions.

Basic Information

Product Name	Ioversol
CAS No.	133352-44-0
Molecular Formula	C24H36I3N3O9
Molecular Weight	807.18 g/mol
Synonyms	Ioversolum; Optiray; 5-[N-(2-Hydroxyethyl)acetamido]-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide; Ioversolum; Ioversolum [INN-Latin]; Ioversolo [DCIT]; Ioversolum [INN-Spanish]; Ioversolum [INN]; Ioversol [USAN]; Ioversol [INN]; Ioversol [BAN]; Ioversol [JAN]
EINECS	Contact for details

Quality Control

Our Ioversol is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes rigorous analytical testing including HPLC for assay and impurity profiling, residual solvent analysis, and tests for related substances. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and safety parameters is provided with each shipment to ensure traceability and regulatory compliance for our pharmaceutical clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Iodine Content	46.8% - 48.0%
pH (5% Solution)	5.0 - 7.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.