Description

1,3-Dichloro-2-Fluoro-5-Iodobenzene is a high-purity halogenated benzene derivative, a key building block in advanced organic synthesis. Its precise substitution pattern makes it an invaluable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and in the creation of organocatalysts for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules and liquid crystals, due to its halogenated aromatic structure.
• Fluorine Chemistry: Acts as a valuable substrate for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce the iodine handle for diversification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity halogenated intermediates.

Basic Information

Item	Detail
Product Name	1,3-Dichloro-2-Fluoro-5-Iodobenzene
CAS No.	133307-08-1
Molecular Formula	C6H2Cl2FI
Molecular Weight	304.89 g/mol
Synonyms	2-Fluoro-1,3-dichloro-5-iodobenzene; 1,3-Dichloro-2-fluoro-5-iodobenzene; 5-Iodo-1,3-dichloro-2-fluorobenzene; 2-Fluoro-5-iodo-1,3-dichlorobenzene; Benzene, 1,3-dichloro-2-fluoro-5-iodo-; 133307-08-1; DCIFIB
EINECS	Contact for details

Quality Control

Our 1,3-Dichloro-2-Fluoro-5-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural identity. A Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.