Description

Toxoplasma P22 Antigen is a highly purified, recombinant protein derived from the major surface antigen of Toxoplasma gondii. This antigen is critical for the development of sensitive and specific diagnostic assays for toxoplasmosis, a globally significant parasitic infection. It is an essential raw material for in-vitro diagnostic (IVD) manufacturers, research institutions, and biopharmaceutical companies engaged in immunology and infectious disease studies.

Application

• Immunodiagnostic Assay Development: Primary component for ELISA, Western Blot, and Lateral Flow Assay kits for detecting Toxoplasma gondii antibodies (IgG, IgM, IgA).
• Clinical Research & Serology: Used as a coating antigen or capture reagent in research studies to understand host immune response and disease epidemiology.
• Vaccine Research: Serves as a key antigen in the research and development of potential subunit vaccines against toxoplasmosis.
• Quality Control & Reference Standards: Employed as a positive control or calibrator in the quality assurance of commercial diagnostic kits.
• Academic & Pharmaceutical R&D: Fundamental tool for basic research on parasite biology, host-pathogen interactions, and novel therapeutic target identification.

Basic Information

Product Name	Toxoplasma P22 Antigen
CAS No.	133134-61-9
Molecular Formula	Contact for details
Molecular Weight	~22 kDa (Recombinant Protein)
Synonyms	Toxoplasma gondii P22 Antigen; T. gondii P22 Surface Antigen; P30 Antigen; SAG1-Related Sequence 2 (SRS2) Protein; Major Surface Antigen P22; Recombinant Toxoplasma P22 Protein; T. gondii Diagnostic Antigen; P22 (Toxoplasma)
EINECS	Contact for details

Quality Control

Our Toxoplasma P22 Antigen is produced under stringent conditions to ensure high batch-to-batch consistency and optimal performance in diagnostic applications. Each lot undergoes comprehensive analytical testing, including SDS-PAGE, Western Blot analysis, and functional ELISA validation to confirm identity, purity, and immunoreactivity. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with ISO 13485 standards for IVD raw materials.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted aliquots should be stored at -70°C to -80°C and avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE & Western Blot)	Single band at ~22 kDa, reactive with positive human sera
Purity (by SDS-PAGE)	> 95%
Protein Content (BCA/Lowry)	> 1 mg/vial
Endotoxin Level (LAL)	< 1.0 EU/μg
Functional Activity (ELISA)	Reactive with standard Toxoplasma-positive IgG/IgM controls
Solubility	Soluble in PBS or other aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.