Description

2H-1-Benzopyran-4-Propanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-7-Methoxy-2-Oxo- is a specialized, high-purity chemical building block of significant importance in advanced organic synthesis. This compound, with CAS number 133083-34-8, is valued for its role as a protected amino acid derivative, enabling precise molecular construction. It is primarily required by research institutions and pharmaceutical development companies engaged in the synthesis of novel therapeutic agents and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex drug candidates, particularly in medicinal chemistry research.
• Peptide Synthesis: Used in Solid-Phase Peptide Synthesis (SPPS) as an Fmoc-protected amino acid analog for constructing modified peptide sequences.
• Chemical Biology Research: Employed in the development of molecular probes and tools to study biological pathways and protein interactions.
• Process Development: Serves as a key starting material or intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for the exploration of new synthetic methodologies and heterocyclic chemistry.
• Custom Synthesis: A foundational component for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	2H-1-Benzopyran-4-Propanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-7-Methoxy-2-Oxo-
CAS No.	133083-34-8
Molecular Formula	C28H25NO7
Molecular Weight	487.50 g/mol
Synonyms	Fmoc-4-methoxy-2-oxo-1,2-dihydroquinoline-3-alanine; Fmoc-(4-MeO-2-oxo-1,2-dihydroquinolin-3-yl)-Ala-OH; 3-(Fmoc-Amino)-7-methoxy-2-oxo-2H-chromene-4-propanoic Acid; (2-Oxo-7-methoxy-4-(2-carboxyethyl)-2H-chromen-3-yl)carbamic acid 9H-fluoren-9-ylmethyl ester; Fmoc-3-amino-7-methoxy-2-oxo-2H-1-benzopyran-4-propanoic Acid; 3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-7-methoxy-2-oxo-2H-1-benzopyran-4-propanoic Acid
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-4-Propanoic Acid derivative is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccant use and storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.