Description

4-(Benzyloxy)-3-Fluorophenylboronic Acid is a specialized organoboron compound, specifically a fluorinated phenylboronic acid derivative. This chemical is a critical building block (synthon) in modern synthetic chemistry, valued for its role in forming carbon-carbon bonds. It is primarily utilized by pharmaceutical R&D and agrochemical laboratories for the synthesis of complex molecules, including potential drug candidates and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl structures, a common motif in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate: Serves as a precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems.
• Agrochemical Research: Used to create novel compounds for crop protection agents, leveraging the stability and reactivity of the boronic acid group.
• Material Science: Employed in the development of organic light-emitting diodes (OLEDs) and other advanced polymeric materials.
• Chemical Biology & Proteomics: Can be utilized in the design of molecular probes and sensors due to its specific binding affinity.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical producers offering bespoke synthesis services.

Basic Information

Product Name	4-(Benzyloxy)-3-Fluorophenylboronic Acid
CAS No.	133057-83-7
Molecular Formula	C13H12BFO3
Molecular Weight	246.05 g/mol
Synonyms	(4-(Benzyloxy)-3-fluorophenyl)boronic acid; 3-Fluoro-4-(phenylmethoxy)benzeneboronic acid; 4-Benzyloxy-3-fluorobenzeneboronic acid; B-[4-(Benzyloxy)-3-fluorophenyl]boronic acid; 3-Fluoro-4-benzyloxybenzeneboronic acid; 4-(Benzyloxy)-3-fluoroboronic acid benzene
EINECS	Contact for details

Quality Control

Our 4-(Benzyloxy)-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.