Description

4-Benzyloxy-3-Fluoro-Bromobenzene is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates halogen and ether functionalities, enabling precise chemical modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for constructing sophisticated ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs), due to its conjugated aromatic system.
• Custom Chemical Synthesis: Provides a versatile scaffold for contract research organizations (CROs) and custom synthesis houses to build bespoke molecules for client projects.
• Academic Research: A valuable reagent for university laboratories studying reaction mechanisms, heterocyclic chemistry, and the introduction of fluorine into organic molecules.

Basic Information

Product Name	4-Benzyloxy-3-Fluoro-Bromobenzene
CAS No.	133057-82-6
Molecular Formula	C₁₃H₁₀BrFO
Molecular Weight	281.12 g/mol
Synonyms	1-Bromo-4-(benzyloxy)-3-fluorobenzene; 3-Fluoro-4-benzyloxybromobenzene; 4-(Benzyloxy)-3-fluoro-1-bromobenzene; 3-Fluoro-4-(phenylmethoxy)bromobenzene; Benzene, 1-bromo-4-(phenylmethoxy)-3-fluoro-; (3-Fluoro-4-bromophenoxy)methyl]benzene
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-3-Fluoro-Bromobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and oxidizing agents. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.