Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-(Acetylamino)-, (1R,2S,4R)-Rel- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid norbornene core and functionalized carboxylic acid group make it a valuable precursor for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research institutions and pharmaceutical companies for applications in medicinal chemistry, asymmetric catalysis, and the development of novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring stereochemical control.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize specialized ligands for transition metal catalysts employed in enantioselective reactions.
• Advanced Material Monomer: Serves as a building block for polymers and resins with unique thermal or mechanical properties derived from the strained norbornene structure.
• Academic & Industrial Research: A valuable tool compound for methodological studies in organic synthesis and chemical biology.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, agrochemicals, and specialty chemicals.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-(Acetylamino)-, (1R,2S,4R)-Rel-
CAS No.	133007-78-0
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	(1R,2S,4R)-rel-2-Acetamido-5-norbornene-2-carboxylic Acid; rel-(1R,2S,4R)-2-(Acetylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic Acid; 2-Acetamido-2-carboxy-5-norbornene; N-Acetyl-5-norbornene-2-carboxylic Acid Amine; Norbornene Derivative CAS 133007-78-0; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 2-(acetylamino)-, (1R,2S,4R)-rel-; Chiral Norbornene Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality management protocols. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your research and development documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified for the supplied grade.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.