Description

3,5-Difluoro-4-(trifluoromethyl)phenylacetic acid is a high-value fluorinated aromatic building block. This compound matters as a critical intermediate for synthesizing advanced pharmaceuticals and agrochemicals, where its unique fluorine substitution pattern imparts desirable metabolic stability and lipophilicity. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the fluorine atoms for enhanced bioactivity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Polymer Chemistry: Acts as a monomer or modifier for introducing fluorine functionality into specialty polymers to alter surface properties and chemical resistance.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and other transformations to construct complex, fluorinated molecular architectures for various R&D applications.

Basic Information

Product Name	3,5-Difluoro-4-(trifluoromethyl)phenylacetic Acid
CAS No.	132992-26-8
Molecular Formula	C9H5F5O2
Molecular Weight	240.13 g/mol
Synonyms	[2-(3,5-Difluoro-4-(trifluoromethyl)phenyl)]acetic Acid; 2-(3,5-Difluoro-4-(trifluoromethyl)phenyl)acetic Acid; 3,5-Difluoro-4-(trifluoromethyl)benzeneacetic Acid; α-(3,5-Difluoro-4-(trifluoromethyl)phenyl)acetic Acid; (3,5-Difluoro-4-(trifluoromethyl)phenyl)acetic Acid; 132992-26-8; DFTPA; 4-(Trifluoromethyl)-3,5-difluorophenylacetic Acid
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-(trifluoromethyl)phenylacetic acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.