Description

Nuclear Autoantigenic Sperm Protein (NASP) is a specialized histone chaperone protein that plays a critical role in chromatin assembly and remodeling during the cell cycle, particularly in spermatogenesis. This high-purity protein is essential for advanced research in reproductive biology, oncology, and epigenetics, providing a reliable tool for studying chromatin dynamics and gene regulation. It is primarily utilized by biopharmaceutical R&D teams, academic research institutions, and diagnostic developers focused on fertility studies, cancer biomarker discovery, and chromatin-related therapeutic targets.

Application

• Biomedical Research: A key reagent for investigating chromatin assembly, histone transport, and cell cycle regulation in mammalian cells.
• Reproductive Biology Studies: Used as a target antigen in fertility research to understand spermatogenesis and related autoimmune responses.
• Oncology Research: Employed in cancer studies to explore the role of NASP in tumor cell proliferation and as a potential biomarker.
• Diagnostic Development: Serves as a critical component in the development of immunoassays and diagnostic kits for male infertility and certain cancers.
• Epigenetics & Drug Discovery: Used in high-throughput screening assays to identify novel compounds that modulate chromatin structure and function.
• Antibody Production: Acts as a high-quality immunogen for generating specific polyclonal and monoclonal antibodies.

Basic Information

Product Name	Nuclear Autoantigenic Sperm Protein
CAS No.	132989-56-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NASP; Nuclear Autoantigenic Sperm Protein; Histone H1-binding protein; NASP_HUMAN; sNASP; tNASP; Autoantigenic sperm protein; Nuclear autoantigenic sperm protein (histone-binding)
EINECS	Contact for details

Quality Control

Our Nuclear Autoantigenic Sperm Protein is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including purity assessment by SDS-PAGE and HPLC, to ensure high biological activity and consistency. Certificates of Analysis (COA) detailing identity, purity, and endotoxin levels are provided to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to reach room temperature before opening to minimize moisture absorption. Aliquot reconstituted protein to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Single band corresponding to NASP
Purity (HPLC)	≥ 95%
Protein Content (BCA)	≥ 90%
Biological Activity	Confirmed by functional assay
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.