Description

Lysosomal Membrane Glycoprotein Lep100 is a key transmembrane protein associated with the lysosomal membrane, playing a crucial role in intracellular trafficking and lysosomal biogenesis. This high-purity biochemical is essential for advanced research into lysosomal function, autophagy, and related cellular pathways. It is primarily utilized by research institutions and biotechnology companies focused on cell biology, neurodegenerative disease research, and the development of targeted therapeutic strategies.

Application

• Biochemical Research: Used as a critical reagent in studies of lysosomal membrane dynamics, protein sorting, and vesicular transport mechanisms.
• Cell Biology Studies: Essential for investigating autophagy, lysosomal storage disorders, and intracellular degradation pathways.
• Antibody Production: Serves as a purified antigen for generating specific monoclonal or polyclonal antibodies for diagnostic and research applications.
• Drug Discovery & Target Validation: Employed in screening assays and target identification for diseases involving lysosomal dysfunction, such as certain neurodegenerative conditions.
• Proteomics & Protein Interaction Analysis: Used in pull-down assays, co-immunoprecipitation, and mass spectrometry to map protein-protein interaction networks.
• Diagnostic Development: Potential use as a component in developing diagnostic tools for lysosome-related pathologies.

Basic Information

Product Name	Lysosomal Membrane Glycoprotein Lep100
CAS No.	132965-98-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Lysosome-associated membrane glycoprotein 1 (LAMP-1) fragment; LEP100; Lysosomal glycoprotein 120; LGP120; CD107a antigen; LAMP1; Lysosome-associated membrane protein 1; LAMP-1
EINECS	Contact for details

Quality Control

Our Lysosomal Membrane Glycoprotein Lep100 is produced and handled under stringent quality management protocols to ensure batch-to-batch consistency and biological activity. Each lot is subjected to rigorous analytical testing, including purity assessment and functional characterization. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific activity is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into single-use vials to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Corresponds to reference standard
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 1.0 mg/vial
Endotoxin Level (LAL)	< 1.0 EU/μg
Biological Activity	Confirmed by functional assay (e.g., antibody binding)
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.