Description

N(Alpha)-((Biotinylamido)Hexanoyl)-Neuropeptide Y is a biotinylated derivative of the important neuropeptide Y (NPY), designed for high-affinity detection and isolation applications. This modified peptide is critical for researchers requiring precise targeting and visualization of NPY receptors and pathways in complex biological systems. It is primarily utilized in pharmaceutical R&D, biochemical assays, and advanced proteomics studies for investigating metabolic regulation, appetite control, and cardiovascular function.

Application

• Biomarker Discovery & Proteomics Research: Used as a tagged ligand for the isolation and identification of NPY receptor complexes and interacting proteins.
• High-Sensitivity Immunoassays: Serves as a critical component in ELISA, Western blot, and other assay formats for the detection and quantification of NPY and its receptors.
• Affinity Purification & Pull-Down Assays: The biotin tag enables efficient capture using streptavidin/avidin matrices for purifying specific binding partners.
• Cellular Imaging & Localization Studies: Employed in fluorescence microscopy and flow cytometry (when conjugated to fluorophores via biotin) to study receptor distribution and internalization.
• Drug Discovery & Screening: Acts as a tool compound in high-throughput screening (HTS) platforms to identify novel modulators of NPY receptor activity.
• Neuroscience & Endocrinology Research: Fundamental for studying the role of NPY in energy homeostasis, stress response, anxiety, and related disorders.

Basic Information

Product Name	N(Alpha)-((Biotinylamido)Hexanoyl)-Neuropeptide Y
CAS No.	132964-54-6
Molecular Formula	C192H290N56O57S
Molecular Weight	4273.7 g/mol
Synonyms	Biotinylated Neuropeptide Y; Biotin-NPY; Biotinyl-Neuropeptide Y; NPY-Biotin; Neuropeptide Y (Biotinylated); Nα-((6-(Biotinamido)hexanoyl))-Neuropeptide Y; [Biotinamidocaproyl]Neuropeptide Y; Biotinamidocaproyl-NPY
EINECS	Contact for details

Quality Control

Our N(Alpha)-((Biotinylamido)Hexanoyl)-Neuropeptide Y is manufactured under strict quality systems. Each batch is characterized and tested to ensure high purity and consistent biological activity, suitable for sensitive research applications. Comprehensive analytical data, including purity by HPLC and mass spectrometry confirmation, is provided. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -80°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Biological Activity	Confirmed by binding assay (Data on COA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.