Description

Nrp-1 Protein CAS NO 132866-76-3 is a high-purity, biologically active recombinant protein that plays a critical role in neurovascular development and signaling pathways. Its primary value lies in enabling advanced life science research and therapeutic development, particularly in the fields of neuroscience, oncology, and regenerative medicine. This protein is essential for researchers and developers in pharmaceutical R&D, academic institutions, and biotechnology companies requiring reliable, high-quality reagents for cell culture, assay development, and drug discovery programs.

Application

• Neuroscience Research: Used as a key reagent in studies of neuronal guidance, axon growth, and synapse formation.
• Angiogenesis Studies: Employed in vascular biology research to investigate blood vessel formation and tumor angiogenesis.
• Cell Culture & Differentiation: Serves as a growth factor supplement in specialized media for stem cell and primary cell culture.
• Drug Discovery Screening: Acts as a target protein in high-throughput screening assays for developing novel therapeutics in oncology and neurology.
• Biomarker Development: Utilized in the development of diagnostic assays and as a standard for quantifying Nrp-1 levels in biological samples.
• Receptor-Ligand Interaction Studies: Essential for binding studies and characterizing signaling pathways involving VEGF and semaphorin families.

Basic Information

Product Name	Nrp-1 Protein
CAS No.	132866-76-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Neuropilin-1; NRP1; BDCA4; CD304; VEGF165R; Neuropilin-1 Precursor; Soluble Neuropilin-1; sNRP1; NRP-1; Vascular Endothelial Cell Growth Factor 165 Receptor
EINECS	Contact for details

Quality Control

Our Nrp-1 Protein is manufactured under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot undergoes rigorous quality testing, including purity analysis, endotoxin testing, and functional activity assays. Certificates of Analysis (COA) detailing purity, concentration, biological activity, and sterility are provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Purity (SDS-PAGE)	> 95%
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Determined by cell-based assay
Sterility	Sterile filtered (0.2 µm)
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.