Description

Cystatin Beta CAS NO 132848-18-1 is a low molecular weight protein belonging to the cystatin superfamily of cysteine protease inhibitors. This compound is critical for regulating proteolytic activity in biological systems, ensuring cellular homeostasis and function. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic sectors for studying protease-related pathways and developing therapeutic and analytical applications.

Application

• Biomedical Research: Used as a specific inhibitor in enzymatic studies to investigate the role of cysteine proteases in cellular processes, disease models, and signal transduction.
• Pharmaceutical Development: Serves as a reference standard or active pharmaceutical ingredient (API) intermediate in the development of therapies targeting conditions like neurodegenerative disorders, cancer, and inflammatory diseases.
• Diagnostic Reagent Manufacturing: Employed in the formulation of diagnostic kits and assays for the detection and quantification of specific protease activities, which are biomarkers for various pathologies.
• Cell Culture & Biotechnology: Applied in bioprocessing to control unwanted proteolytic degradation, thereby enhancing the yield and stability of recombinant proteins and other biological products.

Basic Information

Product Name	Cystatin Beta
CAS No.	132848-18-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CSTB; Cystatin B (Human); Stefin B; Liver Thiol Proteinase Inhibitor; CPI-B; Cystatin, Brain; MGC117344; Cystatin BN; Neutral Cysteine Protease Inhibitor
EINECS	Contact for details

Quality Control

Our Cystatin Beta is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and biological activity, meeting the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), biological activity, endotoxin levels, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity	≥ 90% of stated activity
Endotoxin	< 1.0 EU/mg
Protein Content (UV)	≥ 90%
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.