Description

Gallium(68)-Ethylenediamine-N,N'-Bis(2-Hydroxyphenylacetic Acid) is a bifunctional chelator complex, specifically designed for the stable coordination of the positron-emitting radionuclide Gallium-68. This compound matters because it enables the creation of highly specific and sensitive diagnostic agents for Positron Emission Tomography (PET) imaging. Pharmaceutical researchers and radiochemists need this high-purity precursor for developing novel radiopharmaceuticals targeting various cancers and other diseases.

Application

• Radiopharmaceutical Precursor: Key intermediate for synthesizing Gallium-68 labeled PET imaging agents.
• Oncology Research: Development of targeted PET tracers for cancer detection, staging, and treatment monitoring.
• Cardiology Imaging: Potential use in creating agents for imaging myocardial perfusion or inflammation.
• Neuroimaging Probes: Synthesis of tracers for studying neurological disorders like Alzheimer's or Parkinson's disease.
• Preclinical & Clinical Research: Essential for academic, biotech, and pharmaceutical R&D into new diagnostic compounds.
• Theragnostic Development: Serves as a platform for creating paired diagnostic/therapeutic (theragnostic) agents when linked to appropriate targeting vectors.

Basic Information

Product Name	Gallium(68)-Ethylenediamine-N,N'-Bis(2-Hydroxyphenylacetic Acid)
CAS No.	132830-14-9
Molecular Formula	C₁₈H₁₆GaN₂O₆
Molecular Weight	~429.04 g/mol (for non-radioactive Ga isotope)
Synonyms	Ga-68 EHPG; Gallium-68 EHPG; ⁶⁸Ga-EHPG; Ethylenediamine-N,N'-bis(2-hydroxyphenylacetic acid) Gallium-68 complex; Gallium-68 (Ethylenediamine-N,N'-di-2-(p-hydroxyphenyl)acetic acid); ⁶⁸Ga-EDDHA; Gallium-68 complex of EDDHA
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality control protocols suitable for radiopharmaceutical research. Each batch is characterized to ensure identity, purity, and complexation efficiency. Certificates of Analysis (COA) are provided, detailing critical parameters such as radionuclidic purity, radiochemical purity, and specific activity. Our quality system supports compliance with cGMP guidelines for investigational medicinal products.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at the recommended temperature (typically 2-8°C or as specified on the label). Due to its hygroscopic nature, protect from moisture. Handle and store in accordance with all applicable radiation safety regulations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Radiochemical Purity (TLC/HPLC)	≥ 98.0%
Radionuclidic Purity (Gamma Spectrometry)	≥ 99.9% at calibration time
Specific Activity	Contact for details
pH (in solution)	4.0 - 7.0
Bacterial Endotoxins (LAL)	< 17.5 EU/mL
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.