Description

Blonanserin CAS NO 132810-10-7 is a potent atypical antipsychotic compound belonging to the chemical class of benzisoxazole derivatives. It is primarily valued for its high affinity and selectivity for dopamine D2 and serotonin 5-HT2A receptors, which is central to its therapeutic mechanism. This active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers and research institutions developing treatments for psychiatric disorders such as schizophrenia.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of antipsychotic medications.
• Neuropharmacological Research: A critical reference standard in studies investigating dopamine and serotonin receptor interactions.
• Generic Drug Development: Serves as the core compound for developing generic versions of branded antipsychotic drugs.
• Clinical Trial Material (CTM): Used in the production of batches for clinical studies and bioequivalence testing.
• Analytical Standard: Employed in quality control laboratories for method development, validation, and assay calibration.
• Preclinical Studies: Utilized in animal models to study efficacy, pharmacokinetics, and safety profiles of antipsychotic agents.

Basic Information

Product Name	Blonanserin
CAS No.	132810-10-7
Molecular Formula	C₂₃H₃₀FN₃O
Molecular Weight	383.50 g/mol
Synonyms	Blonanserin; AD-5423; Lonasen; 2-(4-ethylpiperazin-1-yl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine; 4-(4-Fluorophenyl)-2-(4-ethyl-1-piperazinyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine
EINECS	Contact for details

Quality Control

Our Blonanserin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specifications for identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.