Description

3-(4-((tert-Butoxycarbonylamino)Methyl)Phenyl)Propanoic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on peptide mimetics, linker molecules, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and metabolic disease research.
• Peptidomimetic Synthesis: Used to incorporate non-natural amino acid residues into peptide chains to enhance stability and bioavailability.
• Linker Chemistry: Serves as a spacer or linker molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for amines in multi-step synthetic sequences.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and probes for studying biological pathways and target engagement.
• Material Science Research: Potential intermediate for functionalized polymers and advanced organic materials requiring specific aromatic and carboxylic acid functionalities.

Basic Information

Product Name	3-(4-((tert-Butoxycarbonylamino)Methyl)Phenyl)Propanoic Acid
CAS No.	132691-45-3
Molecular Formula	C15H21NO4
Molecular Weight	279.33 g/mol
Synonyms	3-[4-[[(tert-Butoxycarbonyl)amino]methyl]phenyl]propanoic Acid; 3-(4-((Boc-amino)methyl)phenyl)propionic Acid; Boc-AMPPA; N-Boc-4-(2-Carboxyethyl)benzylamine; (3-(4-((((tert-Butoxycarbonyl)amino)methyl)phenyl)propanoic Acid; 4-(2-Carboxyethyl)benzylcarbamic Acid tert-Butyl Ester; BOC-NH-CH2-Ph-CH2-CH2-COOH
EINECS	Contact for details

Quality Control

Our 3-(4-((tert-Butoxycarbonylamino)Methyl)Phenyl)Propanoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.