Description

n-(9H-(2,7-Dimethylfluoren-9-Ylmethoxy)Carbonyl)Leucine is a specialized, high-purity chemical building block designed for advanced research and synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and sophisticated peptide-based materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for applications requiring precise molecular construction.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected leucine derivative, enabling the construction of complex peptide sequences.
• Proteomics Research: Serves as a reagent in biochemical research for studying protein structure, function, and interactions.
• Bioconjugation: Facilitates the site-specific labeling or modification of proteins and other biomolecules for diagnostic and therapeutic applications.
• Material Science: Employed in the development of advanced biomaterials and polymers with tailored properties.
• Academic & Industrial R&D: A valuable tool for exploratory chemistry in both university laboratories and corporate research centers.

Basic Information

Item	Detail
Product Name	n-(9H-(2,7-Dimethylfluoren-9-Ylmethoxy)Carbonyl)Leucine
CAS No.	132684-62-9
Molecular Formula	C24H27NO4
Molecular Weight	393.48 g/mol
Synonyms	Fmoc-Leucine-OH (2,7-Dimethyl); N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine, 2,7-dimethyl-; L-Leucine, N-[(9H-2,7-dimethyl-9-fluorenyl)methoxy]carbonyl]-; N-α-Fmoc-L-leucine (2,7-Dimethyl); 2,7-Dimethyl-Fmoc-Leu-OH; (2S)-2-[[(9H-2,7-Dimethylfluoren-9-yl)methoxy]carbonylamino]-4-methylpentanoic acid; Protected Leucine derivative; Fmoc-Leu(Dimethyl)-OH
EINECS	Contact for details

Quality Control

Our n-(9H-(2,7-Dimethylfluoren-9-Ylmethoxy)Carbonyl)Leucine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.