Description

4-Chloro-5-Cyanoquinoline is a versatile and high-value quinoline derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and cyano functional groups, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active quinoline-based compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic core.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions.
• Dye and Pigment Industry: Acts as an intermediate for synthesizing specialized quinoline-based dyes and colorants.

Basic Information

Product Name	4-Chloro-5-Cyanoquinoline
CAS No.	132586-14-2
Molecular Formula	C10H5ClN2
Molecular Weight	188.61 g/mol
Synonyms	5-Cyano-4-chloroquinoline; 4-Chloroquinoline-5-carbonitrile; Quinoline, 4-chloro-5-cyano-; 132586-14-2; 4-Chloro-5-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Cyanoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and commercial-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.